I get these calls daily, selling some medical alert something or other. Today I pressed "1" for more info, got a person, and told them to remove me from their list and stop the harassing phone calls. Not really hopeful it will work though.
I listened to what seemed like a 5-hour ad for emergency alarms for senior citizens, hung on until I got to talk to somebody, informed them that I was on the DO NOT CALL list, then TOLD them to stop calling me. About 4 days later, I got another call from them.