646 is also an area code for a rural Iowa area about 40 miles southwest of Iowa City. I just don't answer when I don't recognize the number; one idiot has called four times in the last three days. Pressure your phone company for unlimited blocking ability!
WE get calls from this number on our home phone, but we do not answer as we don't know anyone in New York. No messages ever left on answering machine. Very annoying and quite a nuisance.