I finally got fed up with the crap and blocked all areas codes and white listed the ones I actually need/use. For other things like 888 numbers I just send strait to voice mail.. if they need something they can leave a message.
This will lock down all the random calls that are spoofed from exotic places like North Dakota or Maine. I'll finally know when someone is calling me its someone I might actually want to talk to. Stupid it has to come to this, but the FCC and telecom companies aren't doing squat to prevent the companies who are providing the telcom services to these guys. They shouldn't be allowed to spoof their numbers.
Good Luck to the rest of ya. (jailbroken iphone, running blacklist if you are curious to know how i'm blocking all of the area codes).