DEFINITELY do not bother calling back - "pressing 1" does nothing but confirm they reached a human, and give you warm fuzzes temporarily.
What I do - I create a contact on my phone named "Scammer" - each time I get one of these calls, I add the new phone number to the existing contact. If they call back, I immediately know to ignore it.
Sure, they cycle through numbers fairly often, but it's saved me time from wondering whether a call is legit, since I often get legit calls from other area codes on my business phone.
Just got a call from this #, but didn't answer. What a useless piece of *@!) the "National Do Not Call" Registry is since political surveys can still get through. Too bad the government wouldn't do their jobs and start going after these companies.