I've been a CoreStates/First Union/Wachovia/Wells Farg customer for over 25 years. I used to get calls from this number whenever I was driving very long distances on vacation or making large purchases in rapid succession around Christmastime. They have unlocked my card for me in the past once I confirmed purchases.
For the people reporting they don't have a card with them, I strongly suggest that you check for identity theft. Someone may have opened a card in your name. Just because you didn't open a card doesn't mean it's impossible there's a card out there based on your name and identity. Take this seriously.
I only chose "Event Reminder" below because the "Event" was suspicious activity on my card.
The message stated that there was fraudulent activity on my debit card. The message stated that I could call back the number they gave or the number on the card. I chose to call the number on the card and yes, there was fraudulant activity on my debit card. . . Bottom line, this number is legit.
I got a voicemail from this number. They said, "Hello. This is Wells Fargo Fraud Department calling to verify recent activity on your credit card ending in [XXXX]. Please return our call at 877-515-5750. You can also call the number on the back of your card and request to be transferred to fraud prevention." So I called the customer service number on my card and asked for the fraud department. It turned out that there was an attempted charge to my card for $605 at Victoria's Secret. Wells Fargo had recognized the signs of fraud and denied the charge. I said yes, it was a bogus charge, and thanked them for catching it. They killed that card and are sending me another. I don't know why the two posters on here (or one poster with two names) find it so important to insist the number is false--over and over again--but it certainly is legitimate. Just call Wells Fargo customer service and ask for the fraud department.